Category Archive | Debate
November 14, 2007 | Wednesday
Antiviv inconsistencies obvious to all
I recently received an email from a journalist, who despite not being routinely involved in this debate could easily see the flaws in recent antiviv claims:
"The Hadwen Trust have said that a new European Commission report puts the UK at the top of the animal research rankings. However, if you look at the notes on the bottom, you’ll see that the figure they use is not even from the Commission report!
… they said they used the UK estimate for animal research because European figures didn’t account for certain types of research. How the UK figure can therefore be used as a comparison is a bit of a mystery to me!"
See Dr Hadwen Trust website, News, New Statistics: Britain still the animal testing capital of Europe, 9th Nov 2007
Unlike the rest of Europe, the UK counts breeding of GM animals as a procedure meaning that when GM animals aren’t counted we aren’t actually in the top spot. That you have to compare like with like – just because France, for instance, doesn’t count GM animals it doesn’t mean it doesn’t have thousands running around the lab – seems to have passed the folk at DrHT by. However, ‘UK is number 2 in Europe’ doesn’t have quite the same ring to it. It’s sad that one of the supposedly respectable antiviv groups has resorted to these tactics.
The UK collects and publishes the fullest details of animal research undertaken in the world, as well as being acknowledged by the antis as being "at the forefront of cutting edge non-animal research"(1). Add to this that DrHT’s very own Gill Langley recognises that UK animal research is a "very tiny minority of research effort"(2), and the negative comments look very silly indeed!
It would benefit animal welfare more if the DrHT had instead held these facts up as an example to other countries.
I’d actually say that it is a source of pride that the UK is the world leader in conducting top quality animal research that is carefully regulated and fully accounted for.
-----------------------------------------------------
(1) National Anti-Vivisection Society & Lord Dowding Fund for Humane Research (Nov 2002) Monkeys & Men
(2) Gill Langley (17th July 2001) Oral evidence to House of Lords Select Committee on Animals in Scientific Procedures
November 04, 2007 | Sunday
Planet Earth to Jerry Vlasak - the war is over!
Presumably concern for the environment is not something that bothers Jerry Vlasak, the extremist animal rights advocate from the US. He flew 10,000 miles to speak for 10 minutes in a debate on animal research in Dublin last week.
What was remarkable was the man’s ability to make such a bad impression in such a short space of time. Not only was he the only speaker who refused to take questions, much to the frustration of those present, but he managed to spectacularly misjudge the mood of the audience.
Vlasak, who has advocated violence against researchers who use animals, spent most of his speech likening his movement to the French resistance during the Second World War. Such rhetoric seemed absurd in what was an otherwise genuine debate about a difficult ethical issue. Vlasak clearly lives on a different planet to the rest of us.
It was difficult to take seriously Vlasak’s bizarre vision compared to the reality of well-regulated and carefully conducted humane animal research. It conjured up extraordinary visions of commonly used animals in research, such as fruit flies and fish, being overrun by Nazi stormtroopers!
No wonder the other proposed speakers from the UK backed out at short notice. Sharing a platform with a man locked in a mental mind trap from the last century would surely have been an embarrassment.
At the end of the evening, much like a similar debate at Cork University the month before, the vote was overwhelmingly in favour of animal research. Indeed, it was difficult to find anyone hanging around afterwards at the students bar who thought that animal rights was issue at all in Ireland!
October 22, 2007 | Monday
Marmosets, marshmallows and misrepresentation
It was five years ago, in October 2002, that the Chief Inspector released his report Aspects of Non-human Primate Research at Cambridge University. This had been in response to allegations made following an infiltration by the British Union for the Abolition of Vivisection (BUAV).
The sorry story has continued right up to this month. The Home Office has just lodged papers at the High Court appealing against the recent ruling of a judge on one out of four points for which the BUAV took them to court.
What has been lost in this debate is proper publicity for the very high standards of animal care and welfare which are maintained at Cambridge University. It is worth re-visiting the Chief Inspector’s report. He found that:
• The Cambridge facility is generally well managed and provides appropriate standards of accommodation and care for the animals.
• The staff and management have a good ‘culture of care’.
• The standard of record keeping is good.
• The facility seems adequately staffed, both in terms of quantity and quality of staff.
• The veterinary input is exemplary.
The BUAV made dozens of allegations against the University. So many in fact, that the Chief Inspector devoted 55 pages of his report to investigating them all. Many of the allegations made by BUAV were trivial, false or deeply misrepresentative.
In one case, the BUAV suggested that exposure to an unfamiliar cage causes stress in marmosets, measured by a 4-5 fold increase in blood pressure. Anyone with an ounce of medical knowledge would recognise this to be absurd.
In typically mean-spirited fashion, the BUAV accused Cambridge University of causing dental abscesses in monkeys by overfeeding marshmallows. These are used to reward animals in behavioural and cognitive tests. No evidence was given to support this claim. Although it may seem trivial, it demonstrates that the BUAV will make pretty much any allegation they think they can get away with, regardless of the evidence required for the public or politicians to evaluate their claims.
One of the leading vets in the country, with considerable experience in the welfare of non-human primates, has pointed out that this claim is almost impossible to evaluate without further information. For example, what sort of diet was used routinely, and whether there was a regular dental maintenance programme, would have been highly significant in assessing the impact of marshmallows on the dental health of the colony. In fact the Chief Inspector’s report found a ‘complete absence of dental caries in the animals’, and concluded that these occasional problems were age-related and occurred no more frequently at Cambridge University than in other marmoset units.
BUAV got considerable publicity for its infiltration at Cambridge University. Isn’t it time somebody exposed BUAV?
<Wrap up...>
October 08, 2007 | Monday
Shameless spin on court case consequences
The most vitriolic antivivisection group in the UK, the British Union for the Abolition of Vivisection (BUAV) has spun out of control in its account of the single point it won in the court case against the Home Office this July. The Home Office has appealed against the ruling.
In its latest mailing to supporters, the BUAV claims that the government was ‘found guilty of turning a blind eye to the substantial suffering of animals’. No such verdict was made by the judge in the full court transcript. He never claimed that the suffering of animals was not taken into account, but rather that the severity limits for certain experiments were incorrectly assigned when project licences held at Cambridge University were renewed in 2003 (he said they should have been ‘substantial’ rather than ‘moderate’). The Home Office remains clear in their original assessment of this case that changing the severity limit would not itself alter the experience of an animal undergoing regulated procedures.
Despite the rhetoric from the BUAV, the judge said precious little on the wider implications of his ruling, apart from comments on information provision. Here he stated that:
‘…the welfare of animals subjected to experimental procedures is of no little interest to the public at large. It is of importance that the limited information which is made public is accurate. It is also important that Parliament is accurately informed’.
The judge also commented that a reasonably well-informed member of the public or of Parliament should be able to readily understand the general thrust of the categories of severity limits and bands. In fact only the number of project licences granted in each severity band are published every year in the Home Office annual statistics. The severity limits of individual protocols are not routinely published and cannot therefore be said to form a central part of the public debate.
The BUAV claims that the court verdict should mean that ‘many licences for animal testing are not granted’. There does not seem to be any basis for this assertion. The Home Office consider that ‘judgements of animal welfare costs, the level of suffering that may be produced, and the humane endpoints to be applied are determined by the detailed narrative descriptions on the form of application and licence, not by the shorthand severity limits assigned to the protocols or the severity band assigned to the licence’. In other words, the Home Office assesses any potential suffering to the animal on the basis of what is actually expected to happen to the animal. This is obviously sensible.
Home Office licensing of animal experiments is all about judgement. In matters of judgement, there will inevitably be disagreement sometimes. In this case, the judge did not agree with the views of the experts. Fair enough. If that is his view, it must stand unless the Home Office appeal is successful. But it is virtually impossible from such a small and highly selective sample to draw any wider conclusions relevant to animal experiments in general.
The use of monkeys accounts for only a tiny fraction of all scientific procedures involving animals – about 0.14%. Since regulatory toxicology accounts for two thirds of primate use, research purposes are only one third. Whilst neuroscience is an important area for the use of monkeys, brain surgery on monkeys is only one type of procedure – exceptionally rare overall. In this case, the judge selected for consideration only one project licence out of three issued to Cambridge University. For his judgement he referred only to three of the seven protocols in that one project licence. We are therefore talking about an extraordinarily high degree of scrutiny of an extraordinarily small number of experiments.
The fact that the judge did not uphold the three other points made before him by the BUAV, (and gave no leave to appeal), is not surprisingly something that BUAV chooses to ignore!
<Wrap up...>
October 05, 2007 | Friday
Chemistry World falls for antiviv spin
By
Tigger | Filed in
Science /
Debate /
The National Research Council (NRC) recently produced a report titled Toxicity Testing in the Twenty-first Century: A Vision and a Strategy. In it, they outline a plan for utilising new technology to streamline toxicity testing. The plan’s aim is to increase efficiency whilst decreasing costs, time, and numbers of animals used.
The report notes that one of the ‘challenges’ of developing an in vitro test system to evaluate toxicity is "The current inability of cell assays to mirror metabolism in the integrated whole animal." (p5)
They go on to note that targeted testing in the future may be in vitro or vivo:
They could use transgenic species, isogenic strains, new animal models, or other novel test systems…
Whatever system is used, testing protocols would maximize the amount of information gained from whole-animal toxicity testing.
Contrary to what antivivs such as Europeans for Medical Progress have claimed in the wake of the report, animal models will not be fully replaced in the foreseeable future and are in fact likely to be improved to overcome their current shortcomings.
Throughout the report, brief summary, and press release the NRC acknowledges:
(i) that it is the advent of new technology that makes this possible
toxicological evaluation of chemicals is poised to take advantage of the on-going revolution in biology and biotechnology. This revolution is making it increasingly possible to study the effects of chemicals [using non-animal methods]
- NRC: Report in brief, July 2007, p1
(ii) the techniques will take time to develop and validate
The report concludes that substantial benefits will result from achieving the vision but that it will require coordinated efforts and resources over the next several decades
- NRC: Report in brief, July 2007, p4
(iii) that although animal numbers will be reduced, they will not be completely eliminated for the foreseeable future
Over time, the need for traditional animal testing could be greatly reduced, and possibly even eliminated someday, says the report. For the foreseeable future, however, targeted tests in animals would need to be used to complement the in vitro tests, because current methods cannot yet adequately mirror the metabolism of a whole animal.
- NRC press release, 12th June 2007
Unfortunately the magazine Chemistry World seems to have fallen for antiviv spin that all these techniques are already available and properly validated, and can fully replace animal use. The opening sentence of their article attributes an opinion to the NRC that is not apparent from actually reading the report:
Tests on mice, rats, rabbits and guinea pigs to stop harmful chemicals reaching humans were once a necessary evil. But such checks now seem embarrassingly old-fashioned, according to a report on toxicity testing from the US National Research Council
- Chemistry World, ‘A viable alternative’, August 2007
Let’s hope that serious organisations like the Royal Society of Chemistry, which publishes Chemistry World, accurately reflect the subject under consideration in their future publications.
<Wrap up...>
September 30, 2007 | Sunday
Talking Point
Antivivisection groups have been extremely active lobbying in Europe against the use of animals in research. It is important that we get our arguments together and our message across to MEPs. A short summary of the situation in the UK, titled ‘Talking Point on the use of animals in scientific research’ has just been published in the Journal of the European Molecular Biology Organisation.
September 12, 2007 | Wednesday
The reality of research
We see from a new post on the SPEAK website that the monkey named Felix who they were campaigning to save from Oxford University has now died. SPEAK claimed that Felix was been tortured and that he lived in a small cage, although in fact this primate appeared on a BBC documentary allowing people to make their own judgements about how the animal was looked after.
But we should not shy away from the reality of research. Almost all animals are humanely killed after research, usually to study their tissues to gain further information. Animals are not simply research tools, they are sentient beings. It is regrettable that any animal has to be used, and then die, in research. But it would be even more regrettable if research to advance knowledge and potentially help treat or cure people with distressing and disabling diseases such as Parkinson’s or stroke could not go ahead. And we should not strive to keep animals alive for no good reason if it simply makes them suffer.
In true SPEAK style, their initial pronouncements on Felix sounded sinister; as in their message to Oxford University ‘if for any reason you feel it’s in your best interest to kill Felix before you had intended to, then think again. Or if Felix mysteriously dies, then we urge you to think very seriously about this course of action. The British public will take a very dim view on this course of action, should you choose to take it, and at SPEAK we will never forget such conduct’.
But presumably unable to carry through any threat, SPEAK has now decided apparently that Felix is just a symbol.
September 07, 2007 | Friday
Green behind the ears
By
Zebedee | Filed in
Debate /
Media /
The Independent’s Green Goddess columnist Julia Stevenson’s green hue seems to be that of naivete and gullibility. Her latest column says ‘We don’t need to capture wild primates and destroy them in labs’. She’s right: we don’t need to and we don’t do it, because almost without exception primates are bred especially for research. And someone should tell Julia and her antivivisection spinmeisters that apes haven’t been used in the UK research for well over 20 years, or in any EU country since 2000.
That’s not all. Inspired by groups like Animal Defenders International (this is what the National Anti Vivisection Society prefers to call itself, unsurprisingly), she took part in a monkey-in-cage photocall last week. Apparently there were 20 photographers there. Strange we haven’t seen the pictures yet. Maybe they were all undercover police.
Singer Maria Daines was also there, whose dreadful dirge ‘Monkey in a Cage’ (earnest, but naff, lyrics here) is apparently topping indie and rock charts. I don’t follow the charts, but everyone tells me it’s nowhere near the top 20, let alone number one.
Julia is woefully out-of-date on the progress of the antivivisectionists’ Written Declaration in the European Parliament on primate research. She thinks it still has to get 100 more signatures ‘for a ban on primate testing’. Wrong on both counts. It has already received the requisite number of signatures (on the day before Julia’s piece was published) to move to the next stage, which I think means:
• EU President notifies EU Parliament which publishes declaration and names of signatories in the minutes of the relevant sitting. This ‘closes’ the procedure.
• Declaration is forwarded to institutions named together with names of the signatories.
• The EU Commission will probably provide a written answer to the declaration.
This hardly warrants the jubilation in the ADI camp and it certainly falls far short of ‘the end of primate research in Europe’. Jan Creamer, ADI chief executive, trumpeted:
‘This is history in the making and will end the suffering of some 10,000 primates a year in European labs and the adoption of more reliable modern alternatives.’
There is a deadly serious point here. Ending primate research would hamper research into HIV/AIDS, Parkinson’s disease, and malaria – to name but three serious medical problems in which primate studies are indispensible. While we would all wish to see non-animal alternatives ‘adopted’, it’s simply not possible until we have the alternatives, which is a long way off.
So it’s just as well that a Europe-wide ban cannot happen simply on the say so of naïve MEPs swayed by antivivisection songs and stunts.
August 30, 2007 | Thursday
MEPs think deeply about use of primates in research (not!)
By
Haruspica | Filed in
Debate /
The latest European Parliament written declaration proposal from MEPs on stopping use of non human primates has already been noted on this blog.
One might assume that all the MEPs who have signed so far, have of course carefully weighed up the arguments before they signed.
Fat chance!
The declaration states the justification for:
establish(ing) a timetable for replacing the use of all primates in scientific experiments with alternatives
includes
noting that almost all primate species share more than 90% of their DNA with humans and it is acknowledged that the primate species have a capacity to suffer greatly in
captivity.
Whilst the fallacy of using this argument in respect to animal welfare has already been exposed, some MEPs are happy to have it both ways....
Richard Corbett MEP has said, in the context of comparing the proposed European Treaty and the rejected European Constitution:
The DNA of mice and humans is 90% the same ... but the remaining 10% is rather important.
Not what you just signed up to Richard!
August 29, 2007 | Wednesday
Days of (in)action
We cannot help but wonder how many days of action are needed by the antivivisection groups to make their case. No sooner have Animal Aid held their ‘Action Day for Primates’ on 25 August, than the National Anti-Vivisection Society is to demonstrate for ‘International Primate Day’ on 1 September. We didn’t see any media coverage of the Animal Aid event, and we don’t expect much for the NAVS.
Once again we have to listen to the very limited combined weight of expertise of various celebrities like actress Jenny Seagrove and TV presenter Michaela Strachan. One wonders when these people are going to bother to actually find out some of the facts about primate research instead of trotting out the same tired old antivivisection propaganda.
Perhaps those who care to take part in these days of action should take note of the latest posting on the relatively new blog of SPEAK Political, which claims that “we scratch and claw for every piddling little victory whilst allowing the big picture to completely elude us. At our present rate of achievement, in another 100 years we won’t have moved on much from where we are now. No wonder so many of us drift away disillusioned.” SPEAK used to have lots of days of action. Perhaps the animal rights movement depend too much on celebrities and days of action?
August 10, 2007 | Friday
Public interest and the RSPCA
The work of charities is supposed to reflect the public interest. It is for that reason that antivivisection groups cannot become charities.
So we were intrigued to see the statement from the RSPCA that it would be ‘extremely concerned and angry’ if the Home Office figures for the number of animals used in 2006 showed another increase. The increase reflects more research being done into the genetic basis of diseases, and is very much in the public interest if this can be translated into new treatments and cures. It was welcomed by some patient groups.
Charities are also supposed to be publicly accountable. Yet this crude statement from the RSPCA was released with no accompanying explanation.
The RSPCA has generally been seen as a sensible and pragmatic contributor to the debate about the use of animals in research. Its website states that ‘the RSPCA adopts a constructive and practical approach, judging every issue individually, critically questioning the necessity and justification for animal use and striving to reduce the conflict between animals and science wherever possible’.
If every issue is judged individually, then how can the RSPCA make such sweeping statements about the overall animal numbers?
Most sensible organisations accept that the animal numbers themselves are not a good reflection of progress on improving animal welfare, reducing the amount of suffering for the animals, or implementing the 3Rs.
We will ourselves be extremely concerned if the RSPCA starts to campaign beyond its remit. And it risks losing credibility for its work on animal welfare if it is not careful to put out more measured statements than the one recently released.
<Wrap up...>
July 26, 2007 | Thursday
A load of bull
By
Tigger | Filed in
Debate /
Ethics /
Radio 4’s normally excellent Today programme ran a story this morning on Shambo, the TB-positive bullock in Wales, which left something to be desired in the reporting standard. Clearly, the monks at the temple are distressed but there are a few facts that I think need to be borne in mind before allowing claims like the Welsh Assembly have committed an ‘act of desecration against the temple’ and ‘sacrilege against their religion’ to go unchallenged.
The right to practice religious beliefs freely is an important one – but other rights also exist. The reality is that this world has overlapping considerations that make cases like Shambo’s particularly messy.
Based on serious public health considerations, the law of the land has deemed that cattle infected with TB should be slaughtered. As a result of this policy, twenty thousand cattle across the UK are slaughtered every year. Farmers would undoubtedly prefer this not to happen but in the interests of society, their right to make a living gives way. Why then should an exception be made for one bullock?
Some might argue that Shambo’s ‘holy status’ renders him more important than other cattle; but does it render him more important than human lives? TB, thought to have been largely confined to the history books in developed nations, is making a stealthy comeback… and even more worryingly, our ability to cope with infections is being rapidly eroded due to TB’s increasing drug-resistance. It would be deeply remiss of the authorities to allow a bull that they knew to be infected to be exempted from a measure that is there for society’s protection.
Although I believe that the monks’ offer to keep Shambo isolated was a sincere one, mistakes can happen and the stakes here are too great to run the risk.
On a final (and completely different) note, I cannot believe that keeping a bull penned up inside in complete isolation – however luxurious the circumstances – would be desirable in terms of animal welfare.
<Wrap up...>
July 20, 2007 | Friday
Paul McCartney - do as you wish but don't deceive others
By
Haruspica | Filed in
Debate /
Media /
Paul McCartney has said he will stop funding cancer research charities that use animals:
he revealed plans to refuse funding to organisations that practice vivisection, after discovering a number of charities close to his heart advocate the practice
It’s quite right that he follows his own beliefs but not that he uses his celebrity to spread untruths:
There are better alternatives but you’re not allowed to challenge the status quo
This is just not true:
A great deal of cancer research is carried out without using animals. In certain areas, however, animal research remains essential if we are to understand, prevent and cure cancer. (Cancer Research UK)
So where does he get his information? Apparently from Alistair Currie - Senior Research and Campaigns Co-ordinator - People for the Ethical Treatment of Animals. So we know why he is so misguided.
July 16, 2007 | Monday
Lessons from MMR
A surge of publicity has highlighted again the research published in The Lancet in 1998 by Andrew Wakefield and others alleging a link between the MMR vaccine and autism. This has important lessons for the debate about animal research.
In modern western democracies it is inevitable that some individuals who are either practising scientists, or have a science background, will advocate a line of argument that conflicts with the vast bulk of the scientific evidence.
In many cases, we can see a reason why those individuals might favour a particular theory. Those advocating ‘intelligent design’ mostly have a religious perspective. Those opposed to any form of genetic modification often have strong environmental passions. Those who argue that the MMR vaccine is unsafe may be linked to pressure groups comprising parents whose children have developed autism, or even be against all vaccines.
For the field of animal research, the small number of ‘scientists’ who claim that it is inherently flawed usually turn out to have animal rights beliefs. Typical is the group Europeans for Medical Progress (EMP), which is an animal rights group masquerading as a scientific organisation.
The mere fact that some individuals have a scientific background does not mean that a particular line of argument they promote is inherently credible. It remains an important task for the media to discern where the overwhelming weight of scientific evidence and expertise lies, before giving equal balance to extreme minority views.
Another lesson we can learn from the MMR debacle is that any type of research can be flawed if it is badly carried out. EMP currently argues on its website that we should use research tools and methods ‘focusing exclusively on human biology’. Yet that is exactly what Andrew Wakefield and his co-authors did in their research. The alleged link between MMR and autism came from studies of human bowel samples and other data from human tests. The results were flawed and highly misleading. No form of research guarantees the correct answer. Only the animal rights groups focus exclusively on the limitations of animal research. Such short-sightedness and selective use of evidence makes no sense.
<Wrap up...>
July 11, 2007 | Wednesday
A field day for conspiracy theorists
Antivivisection groups have long argued that animal research is perpetuated only by powerful groups with vested interests. A typical quote is that from Peter Hamilton of the Vancouver-based animal rights group Lifeforce: ‘the multi-billion dollar research, drug and chemical industries are entrenched in animal research for economic, legal and political reasons’.
Despite the supposed struggle against these powerful lobby groups acting in conspiracy, it was not that long ago that antivivisection groups in the UK were relatively optimistic. For example, in their newsletter of Summer 2000, the National Anti Vivisection Society boldly proclaimed that ‘the days of animal experimentation are numbered’.
It is no doubt to the dismay of those same antivivisection groups that the government recently revealed in a Parliamentary question by Mr Hancock that ...
it has contributed £45,000 to the cost of leaflets to raise general public awareness about how medicines are developed. The leaflet, titled Where do medicines come from, covers the use of animals in medicines research and testing, as well as clinical trials and licensing. It will be available for patients in around 60 per cent of general practitioner surgeries in England from autumn 2007
So now the government is joining the pharmaceutical companies - so hated by the antivivisectionists - to explain the role of animals in research. Along with, of course, universities, medical research charities, patient groups, medical organisations, biotechnology companies, research councils, independent research institutes, learned societies, regulatory bodies, trade unions, many environmental groups and pretty much any other organisation concerned with science or health you can think of.
There comes a point when we have to ask; if so many people are in on a conspiracy, is it really a conspiracy any longer?
<Wrap up...>